Table 1.
Patients' characteristics, risks of atherosclerosis, and characteristics of CLAD
| VEGF ≥3.2 pg/mL (n = 27) | VEGF ≤3.2 pg/mL (n = 39) | p value | |
|---|---|---|---|
| Age, years | 73 (63–78) | 73 (66–77) | 0.661 |
| Sex | 23 (85%) | 30 (77%) | 0.534 |
| Symptoms within 120 days | 9 (33%) | 15 (38%) | 0.796 |
| Hypertension | 20 (74%) | 32 (82%) | 0.544 |
| Diabetes mellitus | 11 (41%) | 18 (46%) | 0.802 |
| Dyslipidemia | 17 (63%) | 27 (69%) | 0.607 |
| Smoking | 8 (30%) | 9 (23%) | 0.578 |
| Drinking | 11 (41%) | 9 (23%) | 0.174 |
| ICA lesion | 25 (93%) | 36 (92%) | 1.000 |
| Side | |||
| Right | 9 (33%) | 19 (49%) | 0.311 |
| Left | 18 (67%) | 20 (51%) | |
| Bilateral | 3 (11%) | 6 (15%) | 0.727 |
| Antithrombotic agents | 22 (81%) | 27 (69%) | 0.391 |
| Degree of stenosis, % | 73 (61–82) | 80 (69–90) | 0.140 |
| CBF of MCA area of ipsilateral side, mL/100 g/min | 32.6 (31.3–33.6) | 32.6 (28.4–35.3) | 0.749 |
| CBF of MCA area of contralateral side, mL/100 g/min | 33.5 (31.2–35.7) | 33.1 (30.4–35.6) | 0.814 |
CLAD, cerebral large artery disease; VEGF, vascular endothelial growth factor; ICA, internal carotid artery; CBF, cerebral blood flow; MCA, middle cerebral artery.