Table 2.
Comparison of the upstream regulators of IARS2.
| Upstream regulator | Entrez gene name | Predicted state | z-score | P-value |
|---|---|---|---|---|
| TNF | Tumor necrosis factor | Activated | 8.273 | 1.07E-43 |
| Lipopolysaccharide | Lipopolysaccharide | Activated | 8.092 | 8.72E-33 |
| NFκB (complex) | Nuclear factor kappa B | Activated | 6.869 | 3.08E-25 |
| IL1B | Interleukin 1 Beta | Activated | 6.768 | 2.34E-28 |
| Phorbol myristate acetate | Phorbol myristate acetate | Activated | 6.662 | 7.63E-26 |
| SB203580 | SB203580 | Inhibited | −5.124 | 1.61E-14 |
| PD98059 | PD98059 | Inhibited | −4.34 | 1.17E-15 |
| IL1RN | Interleukin 1 receptor antagonist | Inhibited | −3.874 | 7.48E-15 |
| SP600125 | SP600125 | Inhibited | −3.869 | 1.33E-11 |
| CBX5 | Chromobox 5 | Inhibited | −3.742 | 6.92E-06 |