Scheme 3. Synthesis of Target Terminal-Modified ADPR Analogues.
Reagents and conditions: (a) Aldrithiol, imidazole, triethylamine, triphenylphosphine, 20 °C, 16 h; (b) NaI, acetone (precipitation), 0 °C; (c) MgCl2, dimethylformamide, 20 °C, 3–16 h.
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