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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Neurobiol Dis. 2018 Dec 25;124:544–554. doi: 10.1016/j.nbd.2018.12.018

Figure 1: Iba1+ microglial activation is inversely correlated with cerebral blood flow after 3xCHI once daily.

Figure 1:

(A) Representative cortical Iba1 immunohistochemistry of a sham mouse (left) and two 3xCHI injured mice (right) at 4 h post-impact (scale bar = 20 μm, red = Iba1, blue = DAPI). Iba1 labelling intensity modestly increases after 3xCHI. Additionally, animals with low CBF show increased Iba1 intensity and modestly enlarged microglial processes. (B) Quantitative Western blot reveals that Iba1 expression significantly inversely correlates with CBFi measured 4 h after the third CHI (n=8).