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. Author manuscript; available in PMC: 2020 May 15.
Published in final edited form as: Bioconjug Chem. 2019 Apr 22;30(5):1297–1303. doi: 10.1021/acs.bioconjchem.9b00191

Figure 1. Jablonski diagram and mechanisms for photosensitizer-induced ROS generation.

Figure 1.

Photosensitizers in the ground state are excited to a high-energy singlet state, which could subsequently be converted into a triplet state via ISC. This triplet state may further undergo photochemical reactions via either a type I or a type II process to generate ROS. (Abs, absorption; IC, internal conversion; ISC, intersystem crossing; SET, single electron transfer; ET, energy transfer; SOD, superoxide dismutase)