Skip to main content
. Author manuscript; available in PMC: 2020 May 17.
Published in final edited form as: ACS Chem Biol. 2019 Apr 17;14(5):959–965. doi: 10.1021/acschembio.9b00150

Table 1.

Chemical and photoluminescence properties of synthetic pyridyl CTZ and DTZ analogs.

Compound R6 R8 R2 Bioluminescence a
λmax (nm)		 Chemiluminescence b
λmax (nm)		 Water Solubility
(μM)
3a graphic file with name nihms-1022963-t0001.jpg graphic file with name nihms-1022963-t0002.jpg graphic file with name nihms-1022963-t0003.jpg 451 505 1416
3b graphic file with name nihms-1022963-t0004.jpg graphic file with name nihms-1022963-t0005.jpg graphic file with name nihms-1022963-t0006.jpg 497 506 1813
3c graphic file with name nihms-1022963-t0007.jpg graphic file with name nihms-1022963-t0008.jpg graphic file with name nihms-1022963-t0009.jpg 532 555 1711
3d graphic file with name nihms-1022963-t0010.jpg graphic file with name nihms-1022963-t0011.jpg graphic file with name nihms-1022963-t0012.jpg 483 492 1736
3e graphic file with name nihms-1022963-t0013.jpg graphic file with name nihms-1022963-t0014.jpg graphic file with name nihms-1022963-t0015.jpg 450 465 987
3f graphic file with name nihms-1022963-t0016.jpg graphic file with name nihms-1022963-t0017.jpg graphic file with name nihms-1022963-t0018.jpg 518 503 1562
CTZ graphic file with name nihms-1022963-t0019.jpg graphic file with name nihms-1022963-t0020.jpg graphic file with name nihms-1022963-t0021.jpg 455 461 256
DTZ graphic file with name nihms-1022963-t0022.jpg graphic file with name nihms-1022963-t0023.jpg graphic file with name nihms-1022963-t0024.jpg 502 510 131

Note:

a

Determined with 1 nM teLuc in PBS;

b

Triggered by peroxymonocarbonate formed in situ.