Dos Santos 2017.
Methods | Randomised controlled cross‐over trial | |
Participants | Country: Brazil 13 participants (7 men, 6 women); mean age (SD): 56 (18) years; time since stroke not described; educational level 11 out of 13 (85%) elementary school; mean naming accuracy at baseline not described Inclusion criteria: left hemispheric stroke at least 6 months prior and Broca or anomic aphasia Exclusion criteria: dysarthria, apraxia of speech, previous speech and language therapy, any clinically significant or unstable medical or psychiatric disorder, history of substance abuse, neuropsychiatric comorbidities |
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Interventions | Each participant underwent all of the following conditions before and after the Boston Naming Test with an intersession interval of unknown length between each condition: ‐ dual tDCS (A‐tDCS over Broca's area and concurrent C‐tDCS over homologous Broca's area) with 2 mA for 20 minutes ‐ TMS over homologous Broca's area with 1 Hz for 20 minutes, using 90% of the motor threshold ‐ sham tDCS with 2 mA for 20 seconds ‐ sham TMS with 1 Hz for 20 seconds |
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Outcomes | Outcomes were recorded at baseline, and at the end of intervention phase: ‐ performance in picture naming ‐ response time ‐ picture‐naming strategy ‐ response time strategy ‐ total response time |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | High risk | Quote: "The randomization was made by statistic orientation in three weeks ..." |
Allocation concealment (selection bias) | Unclear risk | Not described by the study authors |
Blinding of participants and personnel (performance bias) Objective outcomes | Unclear risk | Objective outcome measures: participants apparently were blinded, blinding of personnel not described by the study authors |
Blinding of outcome assessment (detection bias) Objective outcomes | Unclear risk | Not described by the study authors |
Incomplete outcome data (attrition bias) Objective outcomes | Unclear risk | Objective outcomes: all participants completed the study. No treatment withdrawals, no trial group changes and no major adverse events stated |
Selective reporting (reporting bias) | Unclear risk | All outcomes listed in the 'Methods' section reported, no published protocol could be identified |
Other bias | Low risk | No other bias identified |