ChiCTR‐IOR‐16010297.

Trial name or title	Transcranial direct current stimulation (tDCS) combined semantic navigation training to improve aphasia
Methods	RCT
Participants	Country: China Estimated enrolment: 40 Inclusion criteria: 1) first onset of stroke in the left middle cerebral artery; 2) 2 to 24 weeks after onset; 3) aged 20 to 75 years old; 4) WAB Chinese version: non‐fluent aphasia; 5) Chinese native speakers; 6) right‐handed; 7) did not receive any formal speech training after stroke. Exclusion criteria: 1) dementia; 2) serious comprehension obstacles; 3) severe cognitive dysfunction; 4) dysarthria or speech apraxia; 5) vision and visual space obstacle; 6) hearing disorders; 7) mental disorders; 8) can not sit alone or complete aphasia test; 9) tDCS contraindications; 10) epilepsy
Interventions	4 arms: ‐ A‐tDCS over Broca's area with the cathode on the right shoulder (n = 10) ‐ S‐tDCS with combined semantic navigation training (n = 10) ‐ A‐tDCS over Broca's area with the cathode on the right shoulder + combined semantic navigation training (n = 10) ‐ Dual tDCS (A‐tDCS over Broca's area with the cathode on the Broca's homologue area) + combined semantic navigation training (n = 10)
Outcomes	Outcomes will be recorded at unknown time points Primary outcomes: ‐ WAB AQ ‐ Standard Language Test for Aphasia ‐ Mini‐Cal ‐ naming of trained pictures ‐ naming of untrained pictures
Starting date	30 December 2016 (however, study is not recruiting yet)
Contact information	Jiang Zhongli +86 13851898370 Jiangzh3721@163.com 300 Guangzhou Road, Nanjing, Jiangsu, China
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