NCT00854893.

Trial name or title	Enhance [sic] of language learning with neurostimulation (transcranial direct current stimulation)
Methods	Randomised double blind sham‐controlled cross‐over trial
Participants	Estimated enrolment: 70 people with aphasia due to ischaemic stroke with intact motor cortex at least 9 months since stroke, aged between 18 and 86 years Exclusion criteria: severe head trauma in the past, seizures, cardial pacemaker [sic], metal implants in the head/neck region, severe comorbidity, especially neurologic and psychiatric diseases, intake of illegal drugs, MMSE < 27, neuroactive substances (e.g. antidepressants), pregnancy
Interventions	A‐tDCS or C‐tDCS for 20 minutes or S‐tDCS for 30 seconds during language learning Intensity: 1 mA with the electrodes positioned over the primary motor cortex of language‐dominant hemisphere and the reference electrode over contralateral supraorbital area
Outcomes	Primary outcome measure: ‐ relative change to baseline in learning new words in per cent Time point of measurement: ‐ after the end of intervention period and 1 week after study end
Starting date	October 2009
Contact information	Gianpiero Liuzzi, MD: +49 40 7410 ext 59278, g.liuzzi@uke.de Friedhelm Hummel, MD: +49 7410 ext 53772, f.hummel@uke.de
Notes