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. 2019 May 20;16:45. doi: 10.1186/s12966-019-0809-2

Table 2.

Combined effect of concurrent changes in weight and leisure-time physical activity on all-cause mortality

Change in leisure -time physical activity Change in weighta
Loss (≥5%) Stable (< 5% change) Gain (≥5%)
Person years/death Adjusted HRb 95% CI Person years/death Adjusted HRb 95% CI Person years/death Adjusted HRb 95% CI
All-cause mortality
 Remained active 25,127/1112 1.47 1.37, 1.57 154,446/2879 1.00 Reference 279,598/2204 1.00 0.94, 1.06
 Inactive to active 2763/141 1.51 1.27, 1.79 11,934/298 1.22 1.08, 1.38 21,739/257 1.23 1.09, 1.40
 Active to inactive 2850/282 1.70 1.50, 1.93 9558/391 1.35 1.21, 1.50 16,577/305 1.26 1.12, 1.42
 Remained inactive 1145/106 2.31 1.90, 2.81 3656/132 1.29 1.08, 1.53 5960/122 1.54 1.28, 1.85

Abbreviations: CI confidence interval, HR hazard ratio

aCalculated as change in kilograms between the baseline in HUNT1 and last examination in HUNT2

bAdjusted for age, sex, education (< 10 years, 10 to 12 years, and ≥ 13 years, unknown), smoking status (never, former, current, unknown), alcohol consumption (0 units, 1–4 units, ≥5 units, unknown), insomnia symptoms (no, yes, unknown), and history of cardiovascular disease (no, yes, unknown)