Table 3.
Combined effect of concurrent changes in weight and leisure-time physical activity on cardiovascular mortality
| Change in leisure -time physical activity | Change in weighta | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Loss (≥5%) | Stable (< 5% change) | Gain (≥5%) | |||||||
| Person years/ death | Adjusted HRb | 95% CI | Person years/ death | Adjusted HRb | 95% CI | Person years/ death | Adjusted HRb | 95% CI | |
| Cardiovascular Mortality | |||||||||
| Remained active | 25,127/483 | 1.56 | 1.40, 1.74 | 154,446/1102 | 1.00 | Reference | 279,598/802 | 1.06 | 0.96, 1.16 |
| Inactive to active | 2763/54 | 1.40 | 1.06, 1.84 | 11,934/126 | 1.32 | 1.10, 1.59 | 21,739/96 | 1.28 | 1.04, 1.58 |
| Active to inactive | 2850/123 | 1.70 | 1.41, 2.06 | 9558/191 | 1.60 | 1.36, 1.86 | 16,577/139 | 1.46 | 1.22, 1.75 |
| Remained inactive | 1145/44 | 2.25 | 1.66, 3.05 | 3656/58 | 1.37 | 1.05, 1.79 | 5960/146 | 1.57 | 1.17, 2.12 |
Abbreviations: CI confidence interval, HR hazard ratio
aCalculated as change in kilograms between the baseline in HUNT1 and last examination in HUNT2
bAdjusted for age, sex, education (< 10 years, 10 to 12 years, and ≥ 13 years, unknown), smoking status (never, former, current, unknown), alcohol consumption (0 units, 1–4 units, ≥5 units, unknown), insomnia symptoms (no, yes, unknown), and history of cardiovascular disease (no, yes, unknown)