Table 2.
Description of medical context and infectious disease
| Characteristics | DAP (N = 28) | VAN (N = 44) | p |
|---|---|---|---|
| Reason for ICU admission | .004 | ||
| Cardiac surgery, n (%) | 15 (53.6) | 26 (59.1) | – |
| Vascular surgery, n (%) | 2 (7.1) | 14 (31.8) | – |
| Interventional cardiology or short-term mechanical circulatory support, n (%) | 9 (32.1) | 4 (9.4) | – |
| Mediastinitis, n (%) | 2 (7.1) | 0 (0) | – |
| Primary infectious disease | .045 | ||
| Infective endocarditis, n (%) | 8 (28.6) | 15 (34.1) | – |
| Vascular graft infection, n (%) | 2 (7.1) | 12 (27.3) | – |
| VAD infection, n (%) | 4 (14.3) | 0 (0) | – |
| Surgical site infection, n (%) | 5 (17.9) | 6 (13.6) | – |
| Catheter-related infection, n (%) | 5 (17.9) | 4 (9.1) | – |
| Miscellaneous, n (%) | 4 (14.3) | 7 (15.9) | – |
| Microbiological identification | .002 | ||
| MSSA, n (%) | 7 (25.0) | 4 (9.1) | – |
| MRSA, n (%) | 4 (14.3) | 3 (6.8) | – |
| CNS, n (%) | 13 (46.4) | 9 (20.5) | – |
| Enterococcus, n (%) | 1 (3.6) | 4 (9.1) | – |
| Other Gram-positive cocci, n (%) | 1 (3.6) | 6 (13.6) | – |
| Other strains or non-documented, n (%) | 2 (7.1) | 18 (40.1) | – |
P-values for Fisher exact test. DAP daptomycin, VAN vancomycin, ICU intensive care unit, VAD ventricular assist device, MSSA methicillin-susceptible Staphylococcus aureus, MRSA methicillin-resistant Staphylococcus aureus, CNS coagulase negative staphylococci