Table 3.
Univariate analyses of overall survival and penis cancer-specific survival
| Variables | Overall survival | Penile carcinoma-specific survival | ||||
|---|---|---|---|---|---|---|
| Hazard Ratio | 95% CI | P | Hazard Ratio | 95% CI | P | |
| Age | 1.556 | 0.962–2.517 | 0.071 | 0.796 | 0.450–1.407 | 0.432 |
| T stage | < 0.001 | < 0.001 | ||||
| Tx + Ta + T1 | Referent | – | Referent | – | ||
| T2 | 1.543 | 1.134–2.100 | 0.006 | 1.827 | 1.086–3.074 | 0.023 |
| T3 | 2.200 | 1.601–3.023 | < 0.001 | 3.278 | 1.982–5.422 | < 0.001 |
| T4 | 2.976 | 1.208–7.333 | 0.018 | 5.687 | 1.730–18.701 | 0.004 |
| Lymph nodes status | < 0.001 | < 0.001 | ||||
| Nx | Referent | – | Referent | – | ||
| N0 | 0.367 | 0.180–0.747 | 0.006 | 0.226 | 0.070–0.733 | 0.013 |
| N1-N3 | 0.900 | 0.434–1.866 | 0.777 | 1.384 | 0.431–4.444 | 0.585 |
| Grade | 0.001 | 0.001 | ||||
| G1 | Referent | – | Referent | – | ||
| G2 | 1.332 | 0.961–1.847 | 0.085 | 2.367 | 1.263–4.435 | 0.007 |
| G3 + G4 | 2.020 | 1.402–2.912 | < 0.001 | 3.653 | 1.849–7.217 | < 0.001 |
| Distant metastasis | 4.874 | 3.038–7.818 | < 0.001 | 10.161 | 5.802–17.794 | < 0.001 |
| regional lymph nodes removed | 0.940 | 0.695–1.272 | 0.690 | 1.832 | 1.204–2.790 | 0.005 |
| Surgery | 2.390 | 1.476–3.870 | < 0.001 | 3.304 | 1.657–6.590 | 0.001 |
| LVI | 2.078 | 1.576–2.741 | < 0.001 | 2.741 | 1.786–4.205 | < 0.001 |
SCCP squamous cell carcinoma of the penis; LVI lymphovascular invasion; CI confidence intervals
Significant values in bold, “-” = no data