Fig. 6.

Impact of the lack of IL-5, dblGATA, IL-4R and IL-4R/IL-5 on the thoracic cavity cytokine milieu in L. sigmodontis-infected mice. Cytokine concentrations of IFNγ (a, b), IL-4 (c, d), IL-13 (e, f) and IL-5 (g, h) in the thoracic cavity lavage 71 and 119 days post-L. sigmodontis-infection of wildtype (WT), IL-4R^−/−, dblGATA, IL-5^−/− and IL-4R/IL-5^−/− mice. Results are shown as medians. Differences were analyzed for statistical significance using the Kruskal–Wallis test followed by Dunn’s multiple comparison test. *P < 0.05, **P < 0.01, ***P < 0.001. Data shown in a, c, e, g are pooled from two independent experiments at 71 dpi with 10–16 mice per group. Remaining panels (b, d, f, h) are from one experiment at 119 dpi with 6–10 mice per group