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. 2019 May 20;17:162. doi: 10.1186/s12967-019-1898-z

Table 3.

More than twofold elevated lipid elements of patients with severe acute pneumonia (SAP), acute pulmonary embolism (APE), or acute exacerbation of chronic pulmonary diseases (AECPD) with statistical significance, as compared with healthy control (p < 0.05 or less)

SAP APE AECPD
Elements Folds pvalue Elements Folds pvalue Elements Folds pvalue
PC 18:1/23:1 25.49 0.05 PS30:1 8.12 0.00 PC 18:1/23:1 12.39 0.01
d181So 21.71 0.04 PI 36:3 6.86 0.02 PI 36:3 8.21 0.00
PS30:1 12.38 0.02 PS31:1 5.63 0.00 PS30:1 7.21 0.00
PI 36:3 9.59 0.00 lysoPE19:0 5.09 0.05 lysoPE19:0 6.92 0.03
lysoPS17:1 8.70 0.03 PG30:1 4.89 0.00 lysoPI 22:4 (sn-1) 5.55 0.03
lysoPE19:0 8.66 0.02 PS31:0 4.70 0.00 PC 41:6 5.50 0.03
lysoPI22:6 (sn-1) 7.41 0.01 lysoPS18:2 4.15 0.01 PG30:1 5.26 0.00
PE 40:3 6.96 0.02 PC 16:0/26:0 3.98 0.02 PG31:0 5.21 0.00
PS30:0 6.74 0.03 lysoPC22:0 (sn-1) 3.70 0.04 PE 40:3 5.06 0.00
PE 40:2 6.56 0.00 PE 40:3 3.68 0.01 PE 40:2 4.95 0.00
PC 41:6 6.56 0.03 PS30:0 3.60 0.05 PG31:1 4.86 0.00
PE 40:1 6.19 0.00 PE 40:2 3.52 0.01 lysoPI22:6 (sn-1) 4.83 0.00
PE 42:8 6.02 0.03 PS37:6 3.51 0.03 PE 40:1 4.76 0.00
lysoPE22:6 (sn-1) 5.99 0.05 PE 40:1 3.50 0.01 PS30:0 4.18 0.00
lysoPG14:0 5.90 0.01 PG30:0 3.50 0.00 PE 38:7 4.09 0.00
PE 38:1 5.76 0.00 PG31:0 3.49 0.00 PC 39:4 (18:0/21:4) 4.00 0.03
lysoPS16:0 5.44 0.01 PG31:1 3.47 0.00 lysoPC 15:1 (sn-1) 4.00 0.04
lysoPS15:1 5.44 0.01 lysoPS15:1 3.42 0.01 PC 39:3 (18:0/21:3) 3.95 0.03
PE 39:7 5.33 0.00 PE 39:7 3.27 0.02 PE 38:1 3.90 0.00
PS31:1 5.32 0.00 PC 19:0/21:2 3.24 0.02 PE 40:7 3.82 0.00
PE 38:2 5.22 0.00 PE 42:8 3.13 0.04 PE 36:5 3.67 0.00
PE 40:7 4.86 0.00 lysoPS16:1 3.09 0.01 PE 39:7 3.61 0.00
PG30:1 4.78 0.00 PE 38:1 3.06 0.04 lysoPE19:1 3.61 0.04
PE 38:3 4.60 0.02 PC 19:0/19:0 3.05 0.02 PE 42:8 3.58 0.01
PC39:3 (18:0/21:3) 4.58 0.01 PE 38:7 3.01 0.05 lysoPS18:2 3.44 0.00
PC 39:4 (18:0/21:4) 4.57 0.01 lysoPS17:0 3.01 0.01 PC 39:3 3.39 0.02
PC 39:3 4.46 0.01 lysoPC15:1 (sn-1) 2.87 0.01 PG30:0 3.39 0.00
PS32:0 4.43 0.03 PG34:0 2.84 0.01 PE 38:5 3.33 0.00
PE 40:4 4.30 0.04 PG34:1 2.80 0.01 PE 38:2 3.29 0.01
PG31:0 4.28 0.00 lysoPS19:0 2.74 0.01 lysoPS22:6 3.28 0.05
PE 38:7 4.25 0.00 PG32:0 2.65 0.00 lysoPC 17:1 (sn-1) 3.24 0.04
PG31:1 4.19 0.00 PE 38:3 2.60 0.03 PC 19:0/21:2 3.24 0.03
PE 38:5 4.18 0.01 lysoPC22:6 (sn-1) 2.56 0.01 PC 39:5 (18:0/21:5) 3.20 0.03
PE 36:1 4.10 0.00 lysoPG16:1 2.55 0.04 PS31:1 3.17 0.01
PS32:1 4.07 0.01 PS34:4 2.50 0.02 PE 38:3 3.06 0.01
lysoPI20:2 (sn-1) 4.02 0.02 lysoPC19:0 (sn-1) 2.50 0.01 PE 40:4 3.03 0.02
PE 36:5 3.99 0.00 PG32:2 2.49 0.01 PE 37:6p 3.00 0.01
PE 37:7p 3.97 0.00 lysoPC20:3 (sn-1) 2.48 0.02 PG34:0 2.97 0.00
PE 37:6p 3.83 0.00 PS34:5 2.43 0.03 PG32:0 2.96 0.00
lysoPS18:2 3.83 0.01 lysoPC20:5 (sn-1) 2.40 0.01 PC 39:6 2.87 0.02
PE 35:6p 3.80 0.01 lysoPC16:1 (sn-1) 2.40 0.01 PS31:0 2.85 0.01
PC 39:5 (18:0/21:5) 3.77 0.01 PG32:1 2.40 0.01 PG34:1 2.84 0.01
lysoPS14:0 3.64 0.02 PE 35:5p 2.40 0.02 PG34:5 2.81 0.00
lysoPI19:0 (sn-1) 3.52 0.00 PC39:0 (18:0/21:0) 2.36 0.00 lysoPI20:0 (sn-1) 2.80 0.03
PC 39:6 3.51 0.01 PS34:3 2.35 0.05 PE 35:5p 2.73 0.01
PC39:2 (18:0/21:2) 3.45 0.02 lysoPC18:0 (sn-1) 2.33 0.01 PE 35:6p 2.72 0.01
lysoPE19:1 3.34 0.03 lysoPC20:4 (sn-1) 2.31 0.01 lysoPS20:4 2.71 0.03
lysoPS18:3 3.32 0.01 lysoPC18:3 (sn-1) 2.30 0.03 PE 38:6 2.64 0.00
PG30:0 3.31 0.00 PC 41:6 2.30 0.00 PG32:1 2.52 0.01
PE 40:6 3.22 0.01 PG33:1 2.28 0.00 PE 37:7p 2.51 0.03
PE 35:5p 3.15 0.00 PS36:6 2.27 0.04 PE 36:6 2.48 0.01
PC 19:0/21:2 3.15 0.02 lysoPC20:2 (sn-1) 2.26 0.03 PG32:2 2.47 0.01
PS35:3 3.12 0.01 PE 35:6p 2.25 0.04 lysoPG15:0 2.46 0.04
PC 19:0/19:0 2.99 0.01 lysoPC17:0 (sn-1) 2.22 0.01 PE 40:6 2.44 0.01
PG34:0 2.97 0.02 PC 40:6 2.20 0.00 PS35:3 2.40 0.03
PS34:2 2.94 0.01 PS35:3 2.20 0.02 lysoPC16:1 (sn-1) 2.37 0.04
PE 42:7 2.92 0.04 lysoPC20:0 (sn-1) 2.20 0.03 PS34:3 2.35 0.00
PG32:0 2.92 0.00 lysoPS20:5 2.20 0.03 PG34:4 2.32 0.01
PS37:6 2.89 0.01 PS38:7 2.18 0.01 PS37:6 2.27 0.00
PE 37:5p 2.87 0.02 PC 40:7 2.17 0.00 PE 36:4 2.22 0.01
lysoPC 22:0 (sn-1) 2.80 0.01 PS36:5 2.14 0.05 PG33:0 2.22 0.02
lysoPS19:0 2.77 0.01 lysoPC16:0 (sn-2) 2.12 0.01 PS34:4 2.22 0.00
PG32:2 2.71 0.00 lysoPC15:0 (sn-2) 2.12 0.04 PE 36:1 2.20 0.03
PS34:3 2.68 0.01 PS33:0 2.11 0.02 PE 37:5p 2.20 0.03
PG34:1 2.68 0.00 PC 39:4 (18:0/21:4) 2.09 0.00 PG33:1 2.18 0.01
PS34:4 2.67 0.00 lysoPC 18:1 (sn-1) 2.05 0.02 PC 39:7 2.13 0.01
PE 38:6 2.67 0.01 PG33:0 2.04 0.05 PS37:5 2.10 0.01
PE 37:3 2.66 0.05 PC 40:4 2.00 0.00 PC 37:3 2.09 0.04
PS36:5 2.64 0.01 PG36:2 2.08 0.01
PE 36:6 2.60 0.01 PE 38:4 2.08 0.02
PS34:5 2.58 0.00
PE 38:4 2.53 0.02
PC 39:7 2.49 0.01
PG34:5 2.48 0.01
PG34:4 2.46 0.00
PC 37:4 2.44 0.02
lysoPG16:1 2.43 0.01
PG32:1 2.36 0.00
PC 37:3 2.35 0.02
PE 36:4 2.30 0.01
PE 35:1 2.26 0.04
PS35:2 2.23 0.01
PS33:2 2.23 0.04
PC 40:4 2.19 0.00
PG33:0 2.11 0.02
PE 39:6 2.11 0.02
PC 40:6 2.11 0.00
lysoPG18:3 2.08 0.04
PC 40:5 2.06 0.00
PC 40:8 2.01 0.03