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. 2019 May 20;19:136. doi: 10.1186/s12935-019-0859-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Module analysis of PPI network. The red node represents the up-regulated gene and the blue node represents the down-regulated gene. a Module rank 1. This cluster consists of 32 nodes and 477 edges and has the highest score in those clusters. b Module rank 2