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. 2019 May 20;19:609. doi: 10.1186/s12889-019-6907-x

Table 5.

MS costs by EDSS score

EDSS 0–1
(n = 67)
EDSS 1.5–3.0
(n = 77)
EDSS 3.5–5.5
(n = 34)
EDSS ≥6
(n = 21)
Overall
(n = 199)
Sick leave; mean (SD) 80.25 (334.38) 729.52 (2707.92) 627.91 (2646.44) 0 (0) 416.58 (2030.18)
Annual cost (work absenteeism); mean (SD) 510.89 (2089.42) 1280.35 (4279.86) 561.76 (2810.88) 0 (0) 763.40 (3161.83)
Annual cost of premature retirement due to MS; mean (SD) 1006.27 (4144.32) 5302.33 (12,546.38) 8169.30 (16,952.79) 19,178.96 (17,600.87) 5810.12 (13,158.95)
Annual cost of premature work disability/pensioner due to MS; mean (SD) 0 (0) 2941.80 (14,243.37) 2926.08 (7568.11) 1692.58 (5896.10) 1816.83 (9630.69)
Professional staff cost; mean (SD) 290.15 (1576.30) 679.64 (1406.23) 3246.71 (10,532.42) 1057.14 (1442.27) 1026.93 (4622.00)
Informal support cost; mean (SD) 125.76 (771.81) 320.97 (1274.07) 575.22 (1329.16) 350.36 (1427.77) 301.79 (1160.04)
Use of non-reimbursed devices; mean (SD) 0.39 (3.18) 508.95 (2409.37) 1195.59 (3543.34) 3177.05 (4880.50) 736.60 (2756.47)

EDSS Expanded Disability Status Scale, MS Multiple sclerosis, SD Standard deviation