Table 1.

Energy difference: Wilcoxon signed-rank test on each method pair

Method-pair $N_{\mathit{rot}}$	1,2,3	4	5	6
Uniform-EI	$8.1\times {10}^{-24}$	$4.5\times {10}^{-23}$	$3.5\times {10}^{-17}$	$2.8\times {10}^{-15}$
Uniform-LCB	$4.5\times {10}^{-24}$	$4.5\times {10}^{-23}$	$3.7\times {10}^{-17}$	$2.6\times {10}^{-15}$
EI-LCB	$0.02$	0.44	0.89	0.09

Molecules with three or fewer rotatable bonds ($N_{\mathit{rot}}:1,2,3$) are grouped together due to small sample size. The p-values are rounded to 2 significant figures