Table 2.
Patient and outcome characteristics in the four outcome groups
| Normotensive Pregnancy (NP) (n = 897) | Early-onset Preeclampsia (EPE) (n = 8) | Late-onset Preeclampsia (LPE) (n = 29) | Gestational Hypertension (GH) (n = 35) | |
|---|---|---|---|---|
| Characteristics at inclusion | ||||
| Maternal age, years | 30 (27–33) | 30 (25–36) | 30 (27–34) | 30 (27–33) |
| Pregestational maternal weight, kg | 64 (58–74) | 76 (64–84)* | 66 (62–82) | 65 (59–79) |
| Pregestational maternal height, cm | 166 (161–170) | 166 (163–170) | 166 (165–170) | 167 (162–170) |
| Pregestational BMI, kg/m2 | 23,3 (21–26,8) | 27,3 (23,3-29,8) | 24,1 (22,4-30,2) | 23,6 (22–27,9) |
| Gestational age at assessment, weeks+days | ||||
| First trimester | 12w2d (11w5d-12w5d) | 13w (12w3d-13w2d)* | 11w5d (11w1d-12w5d)* | 12w2d (11w6d-12w5d) |
| Second trimester | 20w2d (19w6d-20w5d) | 21w (20w3d-26w3d)* | 20w5d (20w1d-21w4d)* | 20w2d (19w5d-20w6d) |
| Medical history | ||||
| Diabetes Mellitus | 116 (12,9%) | 2 (25%) | 6 (20,7%) | 6 (17,1%) |
| Thrombophilia | 33 (3,7%) | 1 (12,5%) | 1 (3,4%) | 2 (5,7%) |
| Allergy | 177 (19,7%) | 0 (0%) | 4 (13,8%) | 13 (37,1%)* |
| Obstetric history | ||||
| Intra-Uterine Death | 15 (1,7%) | 0 (0%) | 1 (3,4%) | 1 (2,9%) |
| Intra-Uterine Growth Restriction | 7 (0,8%) | 0 (0%) | 0 (0%) | 1 (2,9%) |
| Nulliparity | 472 (52,6%) | 4 (50%) | 8 (27,6%)* | 14 (40%) |
| Hypertension | ||||
| Family history | 41 (4,6%) | 1 (12,5%) | 1 (3,4%) | 2 (5,7%) |
| Previous pregnancy | 55 (6,1%) | 2 (25%) | 4 (13,8%) | 10 (28,6%)* |
| Outcome characteristics | ||||
| Birth weight, g | 3425 (3145–3734) | 1300 (572–1712)* | 3230 (2690–3656)* | 3405 (3040–3720) |
| Birth weight, percentile | 57,5 (33–77,5) | 7,5 (3,8-48,8) | 63,8 (28,1-79,4) | 52,5 (23,5-82,5) |
| Gestational age at delivery, weeks + days | 39w5d (38w5d-40w3d) | 31w5d (27w-32w5d)* | 37w5d (36w5d-39w6d)* | 39w3d (38w5d-40w5d) |
Data are presented as median (IQR) or n (%)
*p<0,05 was considered significant different from normotensive pregnancy (NP)