Table 3.

Factors associated with antibiotic use: results of univariate and multivariate logistic analysis

	N. total patients	N. patients with at least 1 prescription	%	Unadjusted OR (CI 95%)	P-value	Adjusted ORa (CI 95%)	P-value
Year
2008	379	159	42.0	1		1
2009	267	123	46.1	1.2 (0.9–1.6)	0.3	1.2 (0.9–1.6)	0.3
2010	320	170	53.1	1.6 (1.2–2.1)	0.003	1.5 (1.1–2.1)	0.005
2011	320	160	50.0	1.4 (1.0–1.9)	0.03	1.4 (1.0–1.9)	0.03
2012	353	190	53.8	1.6 (1.2–2.2)	0.001	1.6 (1.2–2.1)	0.002
2013	344	174	50.6	1.4 (1.1–1.9)	0.02	1.4 (1.0–1.8)	0.03
2014	333	165	49.5	1.4 (1.0–1.8)	0.04	1.3 (1.0–1.8)	0.05
2015	368	189	51.4	1.5 (1.1–2.0)	0.01	1.4 (1.0–1.9)	0.02
2016	331	186	56.2	1.8 (1.3–2.4)	< 0.001	1.8 (1.3–2.4)	< 0.001
Sex
Female	1352	656	48.5	1		1
Male	1663	860	51.7	1.1 (0.9–1.3)	0.08	1.1 (1.0–1.3)	0.06
Age
≤2 months	507	233	45.9	1		1
3–11 months	497	218	43.9	0.9 (0.7–1.2)	0.5	1.0 (0.8–1.3)	0.8
1–5 years	760	386	50.8	1.2 (1.0–1.5)	0.09	1.5 (1.2–1.9)	0.001
6–11 years	776	425	54.8	1.4 (1.1–1.8)	0.002	1.7 (1.4–2.2)	< 0.001
≥ 12 years	469	250	53.3	1.3 (1.0–1.7)	0.02	1.6 (1.3–2.1)	< 0.001
Missing	6	4	–	–		–
Length of hospital stay (days)
≤7	1480	696	47.0	1		1
08–30	962	540	56.1	1.4 (1.2–1.7)	< 0.001	1.4 (1.2–1.7)	< 0.001
> 30	571	279	48.9	1.1 (0.9–1.3)	0.5	1.0 (0.8–1.2)	1.0
Missing	2	1	–	–		–
Ward
Medical	1031	463	44.9	1		1
Surgical	810	410	50.6	1.3 (1.0–1.5)	0.02	1.3 (1.1–1.6)	0.01
Medical subspecialty unit	861	449	52.1	1.3 (1.1–1.6)	0.002	1.3 (1.1–1.6)	0.003
Intensive care	313	194	62.0	2.0 (1.5–2.6)	< 0.001	2.4 (1.8–3.2)	< 0.001

^aORs were adjusted for sex, year, age, length of hospital stay, ward type