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. 2019 Feb 25;57(4):207–216. doi: 10.5414/CP203343

Table 4. Descriptive summary of UGE24 and inhibition of glucose reabsorption.

Parameter (units) Total daily dose 5 mg Total daily dose 15 mg
Ertugliflozin 2.5 mg BID Ertugliflozin 5 mg QD Ertugliflozin 7.5 mg BID Ertugliflozin 15 mg QD
UGE24, g n 20 20 21 23
Geometric mean 57.1 52.5 58.6 57.6
%CV 31 34 28 28
Inhibition of glucose reabsorption, % n 20 20 21 23
Arithmetic mean 40.3 38.5 42.0 40.6
%CV 27 29 26 26

Values are geometric mean and geometric %CV for UGE24; or arithmetic mean and arithmetic %CV for inhibition of glucose reabsorption. BID = twice daily; %CV = percent coefficient of variation; n = number of subjects contributing to the summary statistics; QD = once daily; UGE24 = urinary glucose excretion over 24 hours.