Table 4.

Effect of a clay mineral (CM)- based product on the concentration of blood metabolites in dairy cows subjected to a subacute ruminal acidosis (SARA)-feeding phase with 65% concentrates for 1 week

Metabolites	CON	CM	SEM	P-value
Amino acids (µM)
Arginine	75.0	101	6.86	0.09
Glycine	507	620	23.0	0.01
Histidine	86.8	103	6.09	0.07
Isoleucine	116	163	14.9	0.04
Lysine	102	138	12.2	0.04
Methionine	20.3	26.6	1.68	0.04
Threonine	65.6	86.4	6.33	0.05
Biogenic amines (µM)
Asymmetric dimethylarginine	0.66	0.84	0.068	0.04
Dihydroxyphenylalanine	0.086	0.071	0.004	0.01
Dopamine	0.15	0.28	0.002	<0.01
Histamine	0.18	0.13	0.001	<0.01
Methionine-sulfoxide	1.32	0.83	0.213	0.09
Spermine	0.12	0.02	0.020	<0.01
Acylcarnitines (µM)
C2	3.29	5.90	0.8760	0.02
C3	0.34	0.44	0.0400	0.02
C3OH	0.013	0.014	0.0006	0.03
C4	0.129	0.162	0.0172	0.02
C5	0.069	0.092	0.0091	0.02
C5 : 1	0.033	0.044	0.0017	<0.01
C10	0.058	0.046	0.0021	0.02
C10 : 2	0.023	0.025	0.0007	0.05
C12	0.042	0.036	0.0020	0.08
C16 : 1OH	0.005	0.006	0.0003	0.01
Phosphatidylcholines (µM)
PC aa C34 : 2	28.1	36.9	4.09	0.07
PC aa C36 : 4	7.63	9.87	0.766	0.09
PC aa C38 : 5	9.71	12.42	1.146	0.10
PC aa C38 : 6	1.92	2.34	0.151	0.04

CON=control; C=carnitine; PC=phosphatidylcholine; aa=diacyl.

Only a subset of metabolites (with P≤0.10) are presented.