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. 2019 May 14;12:119. doi: 10.3389/fnmol.2019.00119

Figure 6.

Figure 6

Normal readily releasable pool and release probability Lrrc4c−/− TA-CA1 and SC-CA1 pathways. (A,B,E,F) Normalized (A,E) and cumulative (B,F) field EPSP (fEPSP) responses at hippocampal SC-CA1 (A,B) and TA-CA1 (E,F) synapses (2–4 months; male) to repetitive stimulations (20 Hz, 5 s). (C,G) Normal readily releasable pool at Lrrc4c−/− SC-CA1 (C) and TA-CA1 (G) synapses. n = 14 slices from four mice (WT), n = 12 (4; KO) for SR, n = 11 (4; WT), n = 10 (4; KO) for SLM, ns, not significant, Student’s t-test (E: t(24) = 0.9234; p = 0.3650; F: t(19) = 0.0520; p = 0.3650). (D,H) Normal release probability (pr) at Lrrc4c−/− SC-CA1 (D) and TA-CA1 (H) synapses. The release probability was measured by dividing the first fEPSP amplitude by the pool size estimate. n = 14 slices from four mice (WT), n = 12 (4; KO) for SR, n = 11 (4; WT), n = 10 (4; KO) for SLM, ns, not significant, Mann-Whitney test (G) and Student’s t-test (H; G: U = 57; p = 0.2701; H: t(18) = 1.431; p = 0.1695).