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. 2019 Feb;16(1):121–130. doi: 10.20892/j.issn.2095-3941.2018.0125

5.

Correlation between clinicopathological characteristics and BRAFV600E mutation in PTMC

Parameter Case (n=299) BRAF V600E mutation (n=249) BRAF V600E wild-type (n=50) P
CLNM 0.265
 Positive 140 (46.8) 113 (80.7) 27 (19.3)
 Negative 159 (53.2) 136 (85.5) 23 (14.5)
Multifocal
 Yes 143 (47.8) 122 (85.3) 21 (14.7) 0.366
 No 156 (52.2) 127 (81.4) 29 (18.6)
Extrathyroidal extension
 Yes 233 (77.9) 192 (82.4) 41 (17.6) 0.447
 No 66 (22.1) 57 (86.4) 9 (13.6)
LLNM
 Positive 23 (7.7) 22 (95.7) 1 (4.3) 0.075
 Negative 276 (92.3) 227 (82.2) 49 (17.8)
Recurrence
 No 283 (94.6) 234 (82.7) 49 (17.3) 0.088
 Yes 16 (5.4) 15 (93.8) 1 (6.2)