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. Author manuscript; available in PMC: 2020 Apr 23.
Published in final edited form as: ACS Nano. 2019 Apr 4;13(4):4278–4289. doi: 10.1021/acsnano.8b09403

Figure 1. Effects of GQDs on S. aureus biofilms.

Figure 1.

(a-f) Confocal microscopy of S. aureus biofilm grown for 3 days and then treated for 1 day; stains - polysaccharide intercellular adhesin (PIA; green) and bacterial cells (blue). Biofilms grown in TSBG medium in presence of (a) 0 μg/mL (f) 50 μg/mL and (c) 500 μg/mL GQDs. Biofilms grown in PNG medium in presence of (d) 0 μg/mL (e) 50 μg/mL and (f) 500 μg/mL GQDs. Bar graphs of quantified (g) surface coverage, (h) thickness and (i) void size of biofilms analyzed from the z-stack images for each group in (a-f). (j, k) Representative SEM images and their (l) calculated surface coverage of S. aureus biofilms grown in PNG media. Scale bar: 200 μm (a-f), 50 μm (j, k).