Table 1.

Characteristics and genotype frequencies for AGT M235T polymorphism in the included studies

Study	Year	ID	Country	Enthic	Sample size Case/Control	Genotypes and allele distribution
						Cases					Controls
						MM	MT	TT	M	T	MM	MT	TT	M	T
Tiret et al.	1995	1	France	Caucasian	630	741	229	301	100	759	501	258	372	111	888	594
Kamitani et al.	1995	2	Japan	East Asian	103	103	6	31	66	43	163	10	41	52	61	145
Ko et al.	1997	3	China	East Asian	150	338	4	22	124	30	270	4	54	279	62	612
Chen et al.	1998	4	China	East Asian	57	76	4	13	40	21	93	13	31	32	57	95
Sheu et al.	1998	5	China	East Asian	102	145	1	26	75	28	176	1	37	107	39	251
Pastinen et al.	1998	6	Finland	Caucasian	122	122	48	66	37	162	140	53	64	34	170	132
Frossard et al.	1998	7	UAE	Caucasian	40	61	14	18	8	46	34	16	26	19	58	64
Gardemann et al.	1999	8	Germany	Caucasian	1058	511	319	582	157	1220	896	385	585	222	1355	1029
Winkelmann et al.	1999	9	Germany	Caucasian	122	92	38	54	30	130	114	28	53	11	109	75
Batalla et al.	2000	10	Spain	Caucasian	220	200	69	99	52	237	203	64	96	40	224	176
Fomicheva et al.	2000	11	Russia	Caucasian	198	152	63	85	50	211	185	43	75	34	161	143
Olivieri et al.	2001	12	Italy	Caucasian	247	245	63	124	60	250	244	54	76	27	184	130
Xie et al.	2001	13	China	East Asian	106	86	8	29	69	45	167	11	30	45	52	120
Fernández-Arcás et al.	2001	14	Spain	Caucasian	212	180	59	121	32	239	185	34	97	49	165	195
Ermis et al.	2002	15	Turkey	Miscellaneous	102	114	32	48	22	112	92	39	59	16	137	91
Hooper et al.	2002	16	USA	Miscellaneous	110	185	4	29	67	37	163	2	31	67	35	165
Zhu et al.	2002	17	China	East Asian	41	116	2	7	32	11	71	18	47	51	83	149
Zhu et al.	2002	18	China	East Asian	118	106	14	48	56	76	160	10	42	54	62	150
Bis et al.	2003	19	USA	Caucasian	208	717	71	98	39	240	176	215	349	153	779	655
Gu et al.	2003	20	China	East Asian	129	90	12	31	86	55	203	7	30	53	44	136
Ranjith et al.	2004	21	India	Miscellaneous	195	300	24	80	91	128	262	29	127	144	185	415
Zhu et al.	2004	22	China	East Asian	192	98	12	75	105	99	285	8	36	54	52	144
Li et al.	2004	23	China	East Asian	120	80	11	60	49	82	158	14	41	25	69	91
Tobin et al.	2004	24	England	Caucasian	547	505	212	252	83	676	418	197	226	82	620	390
Ren et al.	2005	25	China	East Asian	100	70	2	10	35	14	80	13	26	31	52	88
Araujo et al.	2005	26	Brazil	Caucasian	110	104	46	52	12	144	76	43	51	10	137	71
Renner et al.	2005	27	Austria	Caucasian	1370	733	NA	NA	NA	1537	1203	NA	NA	NA	832	634
Liang et al.	2006	28	China	East Asian	133	154	2	30	101	34	232	10	60	84	80	228
Tsai et al.	2007	29	China	East Asian	735	519	15	195	525	225	1245	5	111	403	121	917
Niu et al.	2008	30	China	East Asian	105	110	8	32	65	48	162	9	47	54	65	155
Zhu et al.	2010	31	China	East Asian	151	127	9	27	115	45	257	20	51	56	91	163
Peng et al.	2011	32	China	East Asian	196	200	14	54	128	82	155	18	86	96	122	278
Konopka et al.	2011	33	Poland	Caucasian	100	95	30	46	24	106	94	22	44	29	88	102
Mehri et al.	2011	34	Tunisia	Miscellaneous	123	144	29	53	41	111	135	53	61	30	167	121
Raygan et al.	2016	35	Iran	Miscellaneous	155	185	42	79	34	163	147	71	85	29	227	143
Bonfim-Silva et al.	2016	36	Brazil	Miscellaneous	153	113	23	69	61	115	191	13	63	37	89	137
				Caucasian	306	142	73	145	88	291	321	34	68	40	136	148
Erbas et al.	2017	37	Turkey	Miscellaneous	117	106	11	104	2	126	108	16	85	5	117	95
Isordia-Salas et al.	2018	38	Mexico	Miscellaneous	242	242	138	98	6	374	110	170	62	10	402	82

NA - not available