Figure 5.

Cumulative log concentration-response curves of methacholine induced contraction of isolated trachea (a) and values (mean±SEM) of EC₅₀, (the effective concentration of methacholine, causing 50% of maximum response) (b) in control rats (C), sensitized animals (S), S treated with dexamethasone (S+D) and two concentrations of alpha linolenic acid (S+ALA), (n=4 for ALA and n=6 for other groups)

Statistical differences between groups S, S+D and S+ALA versus group C; ** P<0.01

Statistical differences between groups S+D and S+ALA versus group S; + P<0.05, +++ P<0.001. The statistical comparisons were made using one way analysis of variance (ANOVA) with Tukey-Kramer’s post-test