Figure 2.

Crocin pretreatment at 200 mg/kg for a week once per day decreased serum levels of AST, and ALT beyond IR-induced liver injury. Data represented as mean±SEM, 8 rats in each group. *P<0.05 and ***P<0.001 significant difference compared to the sham-operated rats and αP<0.05 and βP<0.01 significant difference compared to the IR group. Cr: Crocin pretreatment; IR: Ischemia/reperfusion; S: Sham-operated rats; Cr +IR: Crocin pretreatment+ischemia/reperfusion; AST: Aspartate aminotransferase and ALT: Alanine aminotransferase