Table 2.
Pulmonary impairment and SGRQ scores after treatment among subjects with multidrug-resistant tuberculosis.
| Variables | Total n = 58 (%) |
Surgical resection n = 27 (%) |
No surgical resection n = 31 (%) |
p-Value |
|---|---|---|---|---|
| FVC, % predicted | 0.21 | |||
| 0–30 | 0 | 0 | 0 | |
| 30–59 | 6 (10) | 2 (7) | 4 (13) | |
| 60–79 | 16 (27) | 5 (19) | 11 (35) | |
| ≥80 | 36 (62) | 20 (74) | 16 (51) | |
| Median (IQR) | 92 (73–108) | 100 (82–109) | 81 (67–103) | |
| FEV1, % predicted | 0.01 | |||
| 0–30 | 1 (2) | 0 | 1 (3) | |
| 30–59 | 17 (29) | 3 (11) | 14 (45) | |
| 60–79 | 11 (19) | 8 (30) | 3 (10) | |
| ≥80 | 29 (50) | 16 (59) | 13 (42) | |
| Median (IQR) | 80 (55–101) | 85 (64–100) | 63 (44–100) | |
| FEV1/FVC ratio | 0.37 | |||
| <70 | 24 (41) | 9 (33) | 15 (48) | |
| ≥70 | 34 (59) | 18 (67) | 16 (52) | |
| Median (IQR) | 72 (63–81) | 72 (68–80) | 71 (57–82) | |
| SGRQ scoresa | ||||
| Symptoms | 27.5 (10.3–55.6) | 20.5 (7.5–34.0) | 39.9 (20.8–74.5) | <0.01 |
| Activity | 23.3 (5.3–32.6) | 17.1 (2.6–23.7) | 23.7 (8.6–73.4) | <0.01 |
| Impact | 3.6 (0–13.0) | 2.0 (0–9.6) | 5.1 (0.8–38.3) | 0.01 |
| Total (max 100) | 11.8 (6.3–23.9) | 9.5 (4.6–16.4) | 14.2 (9.4–53.6) | <0.01 |
SGRQ, St. George Respiratory Questionnaire; IQR, interquartile range; FVC, forced vital capacity; FEV, forced expiratory volume. FVC, forced vital capacity; FEV1, forced expiratory volume.
a
Median values with interquartile range.