Table 4.
Results of linear regression analysis for spirometric measures of air flow among post-treatment tuberculosis subjects (n = 58).
| Variable | Pulmonary function testa | SQRG total scorea,b | |||
|---|---|---|---|---|---|
| FEV1% predictedc | FVC% predictedc | FEV1/FVC | PEF | ||
| Age, years | −0.87** | −0.88** | −0.31* | −1.00** | 1.19** |
| Male | −2.58 | −9.0 | 0.31 | 1.74 | 2.94 |
| Follow-up BMI | −0.09 | −0.39 | 0.17 | 0.57 | −0.24 |
| Tobacco use | −0.23 | −0.14 | −1.65 | −1.82 | 4.00 |
| Alcohol use | −17.22 | −13.89 | −8.81* | −7.75 | −8.76 |
| Hepatitis C | −24.49 | −10.03 | −16.14* | −26.27 | 7.17 |
| Prior TB | −16.83* | −12.28* | −7.70* | −18.31* | 12.04 |
| Baseline resistance | |||||
| Pre-XDR/XDR | −1.11 | 2.49 | −1.98 | 7.94 | −4.45 |
| Initial CXR | |||||
| Bilateral | −13.66* | −9.89 | −6.99* | −13.97 | 0.92 |
| Follow-up CXR | |||||
| Fibrosis | −18.7** | −18.5** | −5.47 | −19.44* | 13.99 |
| Cirrhosis | −13.8 | −9.70 | −7.78* | −12.08 | 26.66** |
| Bronchiectasis | −39.7** | −36.36** | −11.34* | −30.32** | 11.60 |
| Pleural adhesions | −9.19 | −5.61 | −4.66 | −12.86 | −0.50 |
| Surgery | |||||
| Yes | 14.74* | 14.78* | 5.23 | 13.32 | −11.78 |
| Segmentectomy | 14.0 | 5.53 | 6.83 | 15.00 | 6.88 |
SGRQ, St. George Respiratory Questionnaire; FVC, forced vital capacity; FEV1, forced expiratory volume; PEF, peak expiratory flow; BMI, body mass index; TB, tuberculosis; CXR, chest radiography; XDR, extensively drug-resistant.
Significant at
p ≤ 0.05,
p ≤ 0.01.
Controlled for age and sex.
Standardized for age, sex, and height.