Table 1.
Functional characterization of the lncRNAs in melanoma
| lncRNAs | Expression | Functional role | Related gene | Role | References |
|---|---|---|---|---|---|
| HOTAIR | Up | Motility invasion gelatin matrix | Oncogene | 25, 26 | |
| MALAT1 | Up | Migration metastasis |
miR‐140 Slug ADAM10 |
Oncogene | 32, 33 |
| BANCR | Up | Migration proliferation |
ERK1/2 JNK MAPK |
Oncogene | 35, 42 |
| SPRY‐IT1 | Up | Proliferation differentiation apoptosis | lipin 2 | Oncogene | 43, 48, 49 |
| ANRIL | Up | Colony formation migration | INK4A INK4B | Oncogene | 6, 57 |
| Llme23 | Up | Malignant phenotypes |
PSF Rab23 |
Oncogene | 58 |
| UCA1 | Up | Migration proliferation |
miR‐507 FOXM1 |
Oncogene | 32, 60 |
| SLNCR1 | Up | Invasion |
MMP9 Brn3a AR |
Oncogene | 60 |
| SAMMSON | Up | Viability oxidative |
MITF
MAPK |
Oncogene | 63 |