Figure 2.

SNRPA depletion inhibits GC cell growth. A, The expression of SNRPA was evaluated by western blot in 5 gastric cancer cell lines. B, The effects of SNRPA knockdown on cell proliferation in AGS and BGC823 cells. The knockdown efficiency of SNRPA was determined by western blotting. C, The effects of SNRPA knockdown on colony formation capacity of AGS and BGC823 cells. D, Soft agar assays was performed in BGC823 cells. Cell colonies were photographed and counted after 2 wk. All the above experiments were repeated at least 3 times. The data represent mean ± SD of 3 independent experiments. *P < .05, **P < .01