Figure 6.

Hox transcript antisense intergenic RNA (HOTAIR) and miR‐124 mediated RCC progression through regulating ST8SIA4 expression. (A and B) The protein and mRNA expression level were measured in 786‐O cells after transfected with HOTAIR and miR‐124 by western blotting and qRT‐PCR. (C and D) The protein and mRNA expression level were measured in 786‐O cells after transfected with siHOTAIR or miR‐124 inhibitor. (E and J) Functional assays were performed to verify HOTAIR mediated the ST8SIA4 expression by competing for miR‐124. Each experiment was independently repeated at least three times. Data were presented as mean ± SD (n = 3). *P < 0.05