Table 2.
Differentially expressed genes involved in the Wnt, Hippo and Fak‐Mapk signalling
| Gene description | GenBank | Fold change | |
|---|---|---|---|
| 19 days vs 12 days | 19 days vs 26 days | ||
| Wnt signalling pathway | |||
| Wingless‐type MMTV integration site family, member 4 (Wnt4) | NM_053402 | 3.857 142 | 2.777 022 |
| Wingless‐type MMTV integration site family, member 10a (Wnt10a) | NM_001108227 | 2.829 97 | 3.435 399 |
| Wingless‐type MMTV integration site family, member 10b (Wnt10b) | NM_001108111 | 2.502 069 | 2.540 512 |
| Frizzled family receptor 1 (Fzd‐1) | NM_021266 | 3.985 11 | NS |
| Frizzled family receptor 2 (Fzd‐2) | NM_172035 | 2.401 284 | 2.705 707 |
| Frizzled family receptor 9 (Fzd‐9) | NM_153305 | NS | 0.223 223 |
| Low‐density lipoprotein receptor‐related protein 5 (Lrp5) | NM_001106321 | 2.265 443 | 4.379 979 |
| Secreted frizzled‐related protein 1 (sFRP‐1) | XM_001072532 | 4.414 605 | 2.725 474 |
| Secreted frizzled‐related protein 2 (sFRP‐2) | NM_001100700 | 4.324 393 | 3.200 82 |
| Glycogen synthase kinase 3 beta (Gsk‐3beta) | NM_032080 | 0.375 044 | 0.432 978 |
| Dickkopf 1 (Dkk‐1) | NM_001106350 | 0.248 414 | 0.432 848 |
| Transcription factor 7, Tell specific (Tcf‐7) | XM_001073458 | 3.831 727 | 2.728 356 |
| Lymphoid enhancer binding factor 1 (Lef‐1) | NM_130429 | 4.583 25 | 2.476 436 |
| Catenin (cadherin‐associated protein), beta 1 (β‐catenin) | NM_053357 | 4.015 773 | 4.265 686 |
| Hippo signalling pathway | |||
| Mammalian sterile 20‐like kinase 1 (MST1) | NM_001107800 | NS | 0.397 01 |
| Large tumour suppressor kinase 1 (LATS1) | NM_01134543 | 3.258 143 | 0.340 747 |
| Yes‐associated protein 1 (YAP1) | NM_001034002 | NS | 3.878 762 |
| Mitogen‐activated protein kinase kinase kinase kinase 1(MAP4K1) | NM_001106243 | NS | 0.459 191 |
| Mitogen‐activated protein kinase kinase kinase kinase 4(MAP4K4) | NM_001106904 | 2.121 188 | 0.262 66 |
| Salvador family WW domain containing protein 1 (Sav1) | NM_001097581 | NS | 0.445 885 |
| MOB kinase activator 1A (MOB1A) | NM_001033891 | 0.329 036 | 0.404 453 |
| Fak‐Mapk signalling pathway | |||
| Focal adhesion kinase(FAK) | NM_013081 | NS | 4.229 253 |
| Extracellular signal‐regulated kinase‐1(ERK1) | NM_017347 | 2.956 338 | 4.425 792 |
| Raf‐1 proto‐oncogene, serine/threonine kinase (Raf‐1) | NM_012639 | NS | 2.729 553 |
| SRC proto‐oncogene, non‐receptor tyrosine kinase (Src) | NM_031977 | 2.545 700 | 3.437 297 |
| c‐Jun N‐terminal kinase (Jnk) | NM_053829 | NS | 4.034 904 |
| P38 mitogen‐activated protein kinase (p38‐Mapk) | NM_031020 | 2.519 176 | 3.411 471 |