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. 2018 Aug 28;51(6):e12515. doi: 10.1111/cpr.12515

Figure 5.

Figure 5

miR‐224‐3p mimic reversed SNHG4‐induced tumour‐promoting effects. (A) MTT analysis of the cell viability after transfection with SNHG4 and (or) miR‐224‐3p mimic in Ssos‐2 and U‐2 OS cell lines. (B) Colony formation analysis of the cell colony abilities after transfection with SNHG4 and (or) miR‐224‐3p mimic in Ssos‐2 and U‐2 OS cell lines. (C) Schematic representation of the binding sites of miR‐224‐3p with WT or Mut 3′UTR of DOCK7. (D) The luciferase activity of WT or Mut 3′UTR of DOCK7 was evaluated after transfection with miR‐224‐3p mimic in Ssos‐2 and U‐2 OS cell lines. (E) MTT analysis of the cell viability after transfection with DOCK7 and (or) miR‐224‐3p mimic for 120 h in Ssos‐2 and U‐2 OS cell lines. (F) Western blot analysis of the expression of DOCK7 protein after transfection with DOCK7 and (or) miR‐224‐3p mimic in Ssos‐2 and U‐2 OS cell lines. Data are the means ± SEM of three experiments. *P < 0.05, **P < 0.01