Figure 5.

(A) Cells were treated with 100 μM DFO at different times (0, 12 and 24 h). DFO markedly enhanced HIF‐1α and CXCR4 mRNA level at 12 and 24 h in BMSCs compared to untreated stem cells. Effect of DFO treatment was decreased by LY294002. ^# P < .01, *P < .001 compared to the control group (n = 3), (One‐way ANOVA). (B) DFO significantly potentiated HIF‐1α and CXCR4 protein expression which These effects were blocked by LY294002 treatment. *P < .001 compared to untreated cells (n = 3), (One‐way ANOVA)