Figure 6.

FBXW7‐induced suppression of NSCLC cell growth, migration and invasion, and EMT were partially reverted by Snai1. FBXW7‐silenced H1299 cell or FBXW7‐overexpressing A549 cell was transfected with Sh‐Snai1 or HA‐Snai1, respectively. These transfected cells were then subject to MTT assay and plate clone formation (A), Western blotting (B), wound healing assay (C), Transwell migration assay (D, upper two panels), Matrigel invasion assays (D, lower two panels). * P < .05, ** P < .01, *** P < .0001; n = 3 repeats with similar results. Values are depicted as the Mean ± SD