Figure 2.

JHY‐A007‐50 inhibits TMEPAI promoter activity. (A) HeLa cells were transfected with pGL3‐TMEPAI promoter plasmid for 24 h, and then were treated with the derivatives of compound JHY‐A007‐89 (5 μM). Cells were treated with 0.1% (v/v) DMSO as the negative control. Results are expressed as the fold activity over the activity of the negative control. Data are presented as the mean ± SD (n = 3). (B) Structure of JHY‐A007‐50 (C) HeLa cells were transfected with a pGL3‐TMEPAI promoter plasmid for 24 h, and then were treated with compound JHY‐A007‐50 at the indicated dose