Figure 4.

The effect of JHY‐A007‐50 on cell viability. (A) The cells (L02, HeLa, MCF‐7, MGC‐803 and HepG2) were collected and cell lysates were analysed by Western blot with antibodies to TMEPAI and β‐actin as a loading control. The quantified result was shown in the below panel. HeLa (B), HepG2 (C), MGC‐803 (D), MCF‐7 (E) and L02 (F) cells were treated with JHY‐A007‐50 (1, 2, 4, 8 μM) for 48 h. Cells treated with 0.1% (v/v) DMSO were used as the negative control. Cell viability was determined by an MTT assay (*.01 < P < .05, **P < .01). The dose‐dependent effects of JHY‐A007‐50 on TMEPAI expression in HeLa, HepG2, MGC‐803, MCF‐7 and L02 cells were shown in the corresponding up panel