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. 2018 Jun 26;51(5):e12467. doi: 10.1111/cpr.12467

Figure 1.

Figure 1

Caspases target components of the nucleocytoplasmic transport and proteins maintaining nuclear integrity. Caspases have been found to cleave at least 8 of 30 proteins of the NPC and importins (Table 1), which leads to the destabilization of active transport. Caspases are depicted as a pair of scissors