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. 2019 May 9;13(5):e0007401. doi: 10.1371/journal.pntd.0007401

Fig 4. B314 expressing Tp0136 variants from Nichols and SS14 strains bind to human fibronectin and laminin.

Fig 4

Binding of Tp0136-expressing B314 to wells coated with human tissue fibronectin was significantly higher than that of the control B314 (V) strain; however, binding facilitated by two alleles of Tp0136 was comparable to this ECM component. Binding of B314 expressing the SS14 Tp0136 to laminin was significantly higher than B314 expressing the Nichols variant. Statistical analysis was conducted using a two-tailed unpaired student t test for unequal variance to determine significant difference between the paired groups and p values calculated (*p<0.05, **p <0.01, ****p<0.0001).