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. 2019 May 17;12:3765–3777. doi: 10.2147/OTT.S193675

Figure 4.

Figure 4

Inhibition of FOXP1 is able to imitate the anticancer effects of miR-605 upregulation in NSCLC cells. (A) H460 and H522 cells were transfected with si-FOXP1 or si-NC. After 72 h of transfection, knockdown of FOXP1 was efficient in H460 and H522 cells, as demonstrated by western blot analysis. *P<0.05 vs si-NC. (B, C) MTT and cell apoptosis assays were conducted to examine the effects of FOXP1 silencing on NSCLC cell proliferation and apoptosis, respectively. *P<0.05 vs si-NC. (D, E) The migratory and invasive capacities of H460 and H522 cells after si-FOXP1 or si-NC transfection were evaluated through transwell migration and invasion assays. *P<0.05 vs si-NC.