Figure 6.

The odontogenic influences of DPM on DPSCs in liquid dentin extract (De). In the liquid dentin extract (DPSCs+De group), DPSCs showed up‐regulated odontogenic markers, including DMP‐1 (A) and DSPP (B) both at the transcript and expression level (G). Meanwhile, early osteogenic markers for ALP were down‐regulated (C) in the DPSCs+De group. During cultivation on the DPM with liquid dentin extract (DPSCs+DPM+De group), ALP(C) and SP7 (E) were down‐regulated. DSPP (B) up‐regulation was accompanied with MEPE (D) down‐regulation, which indicated odontoblast differentiation occurred (*P<.05, **P<.01, ***P<.001, NS=none significance) (n=3)