Table 3.

Effect of binary combination of four appropriate drugs and cisplatin on the death and synergism quotient (SQ) for the three cell lines. Concentration of 1, 0.09, 0.03, 0.0015 and 0.005 mmol L⁻¹ was used for azathioprine, terbinafine, hydralazine, sodium valproate and cisplatin respectively

Drug 1	Drug 2	Cell death			SQ
		A2780‐cis	A2780	HDF	A2780‐cis	A2780
Azathioprine	Terbinafine	60 ± 1	69 ± 0.67	23 ± 0.64	1.5	1.5
Hydralazine	Sodium valproate	52 ± 0.5	68 ± 0.66	34 ± 0.6	1.3	1.5
Azathioprine	Hydralazine	52 ± 0.69	50 ± 0.77	22 ± 0.56	1.3	1
Terbinafine	Hydralazine	59 ± 0.57	62 ± 0.63	17 ± 0.67	1.475	1.35
Terbinafine	Sodium valproate	60 ± 0.5	65 ± 1	27 ± 2	1.5	1.5
Azathioprine	Sodium valproate	58 ± 0.94	64 ± 0.65	25 ± 0.3	1.45	1.39
Cisplatin	Terbinafine	48 ± 0.61	66 ± 0.67	22 ± 0.72	2.4	1.57
Cisplatin	Azathioprine	41 ± 0.69	65 ± 0.88	16 ± 0.58	2.05	1.44
Cisplatin	Hydralazine	33 ± 1	41 ± 0.51	14 ± 0.69	1.65	0.93
Cisplatin	Sodium valproate	34 ± 0.87	43 ± 0.35	9 ± 0.85	1.7	1.05