Table 2.
microRNAs (miRNAs) expression profile in keloid scarring
| Sample | Number (Cases/Controls) | Differential miRNA number (up/down) | Up‐regulated miRNAs | Down‐regulated miRNAs | Methods | Ref. |
|---|---|---|---|---|---|---|
| Skin tissue | 4/3 | 17 (3/14) | miR‐214, miR‐645, miR‐338‐5p, miR‐934, miR‐199a‐5p, miR‐21*, miR‐122*, miR‐186*, miR‐495, miR‐412, miR‐551b*, miRPlus‐F1158, miRPlus‐E1038, miR‐1308 | miRPlus‐E1106, miR‐516b, miRPlus‐E1247 | miRNA microarray | 60, 61 |
| Fibroblast | 3/3 | 9 (3/6) | miR‐152, miR‐23b‐3p, miR‐31‐5p, miR‐320c, miR‐30a‐5p, hsv1‐miR‐H7 | miR‐4328, miR‐145‐5p, miR‐143‐3p | miRNA microarray | 64 |
| Fibroblast | 3/3 | 27 (7/20) | miR‐142‐3p, miR‐1249, miR‐136, miR‐376a*, miR‐140‐5p, miR‐193a‐3p, miR‐1234 | miR‐23a, miR‐574‐3p, let‐7d, miR‐331‐3p, miR‐24, let‐7a, miR‐30e*, miR‐93, let‐7f, miR‐98, miR‐31*, miR‐31, miR‐224, miR‐30a*, miR‐769‐5p, miR‐595, miR‐196b, miR‐452, miR‐182, miR‐196a | miRNA microarray | 65 |
| Skin tissue | 3/3 | 65 (5/60) | miR‐302c, miR‐127‐5p, miR‐21, miR‐424, miR‐122 | let‐7a, miR‐1, miR‐133b, miR‐206, miR‐208, miR‐498, miR‐124, miR‐129‐5p, miR‐130a, miR‐146a, miR‐182, miR‐183, miR‐371‐3p, miR‐375, miR‐378, miR‐92a, miR‐101, miR‐125a‐5p, miR‐128a, miR‐150, miR‐18b, miR‐215, miR‐219‐5p, miR‐23b, miR‐26a, miR‐452, miR‐96, let‐7d, let‐7e, let‐7f, let‐7g, miR‐100, miR‐125b, miR‐137, miR‐141, miR‐142‐5p, miR‐15b, miR‐205, miR‐20b, miR‐218, miR‐223, miR‐302a, miR‐33a, miR‐520g, let‐7b, miR‐126, miR‐16, miR‐17, miR‐185, miR‐195, miR‐20a, miR‐488, miR‐7, let‐7c, miR‐210, miR‐222, miR‐24, miR‐301a, miR‐93, miR‐99a | miRNA PCR array | 62 |
| Skin tissue | 12/12 | 32 (23/9) | miR‐21,miR‐4269,miR‐382,miR‐487b,miR‐155,miR‐98,miR‐127‐3p,miR‐31,miR‐939,miR‐134,miR‐432,miR‐152,miR‐455‐3p,miR‐424,miR‐379,miR‐181b,miR‐132,miR‐494,miR‐199a‐5p,miR‐199a‐3p,miR‐214,miR‐3652,miR‐181c | miR‐203, miR‐205, miR‐200c, miR‐200b, miR‐1246, miR‐222, miR‐3613‐3p, miR‐221, miR‐30b | miRNA microarray | 59 |
| Serum | 9/7 | 37 (17/20) | miR‐3684*,miR‐6800‐3p*,miR‐6796‐3p*,miR‐484, miR‐466, miR‐6891‐5p, miR‐1225‐5p, miR‐6813‐3p*,miR‐6805‐3p*,miR‐382‐5p, miR‐4258, miR‐412‐3p, miR‐1185‐2‐3p, miR‐658, miR‐513a‐5p, miR‐195‐5p, miR‐6801‐3p* | miR‐4254,miR‐6804‐3p*,miR‐4318*,miR‐6765‐5p*,miR‐4317,miR‐6803‐3p*,miR‐1470,miR‐6802‐3p*,miR‐3151‐3p, miR‐6734‐5p*,miR‐1307‐3p,miR‐409‐5p,miR‐5196‐5p*,miR‐491‐3p,miR‐4325*,miR‐4429,miR‐4769‐3p*,miR‐4763‐5p, miR‐6879‐5p*, miR‐6836‐3p | miRNA microarray | 66 |
| Skin tissue | 3/3 | 12 (1/11) | miR‐1290 | miR‐1204, miRPlus‐F1158, miR‐934, miR‐186*, miR‐99b*, miR‐605, miR‐645, miR‐342‐5p, miR‐224*, miR‐551b*, miRPlus‐C1110 | miRNA microarray | 63 |