Table 2.
CSC marker | Progression-free survival (mo) | HR | 95% CI | p-value | |
---|---|---|---|---|---|
EpCAM | Low | 4.2 (1.3–7.2) | 1 | ||
High | 4.7 (3.6–5.7) | 1.10 | 0.58–2.10 | 0.77 | |
CD13 | Low | 4.2 (2.5–6.0) | 1 | ||
High | 4.9 (4.1–5.8) | 1.09 | 0.60–1.98 | 0.77 | |
CD24 | Low | 4.2 (3.1–5.3) | 1 | ||
High | 4.5 (1.1–7.9) | 0.96 | 0.45–2.05 | 0.91 | |
CD44 | Low | 4.0 (2.6–5.4) | 1 | ||
High | 4.7 (2.9–6.4) | 1.15 | 0.57–2.34 | 0.69 | |
CD90 | Low | 5.4 (3.4–7.4) | 1 | ||
High | 4.5 (2.4–6.5) | 1.07 | 0.59–1.94 | 0.82 | |
CD133 | Low | 5.5 (3.9–7.0) | 1 | ||
High | 4.0 (1.7–6.3) | 1.97 | 0.91–4.30 | 0.09 | |
CK8 | Low | 2.6 (0.5–4.7) | 1 | ||
High | 4.5 (2.4–6.5) | 0.70 | 0.24–2.08 | 0.52 | |
SALL4 | Low | 3.9 (1.0–6.9) | 1 | ||
High | 5.4 (3.4–7.4) | 0.73 | 0.38–1.41 | 0.35 | |
ALDH1A1 | Low | 4.9 (3.5–6.4) | 1 | ||
High | 4.7 (3.2–6.1) | 0.96 | 0.53–1.74 | 0.89 | |
Albumin | Low | 5.4 (3.2–7.6) | 1 | ||
High | 4.7 (3.4–5.9) | 1.15 | 0.62–2.11 | 0.66 | |
AFP | Low | 4.9 (3.0–7.3) | 1 | ||
High | 4.1 (3.0–5.2) | 1.32 | 0.69–2.54 | 0.41 |
Data are presented as the median (95% CI).
CSC, cancer stem cell; HR, hazard ratio; CI, confidence interval; AFP, alpha-fetoprotein.