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. 2019 May 16;11:4505–4518. doi: 10.2147/CMAR.S196025

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© 2019 Cao et al.

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HOXA11-AS promotes the proliferation of OS. (A) Down-regulation of HOXA11-AS expression in MG-63 cells could inhibit cell proliferation, while up-regulation of HOXA11-AS expression could promote cell proliferation *P<0.05,**P<0.01. (B) Down-regulation of HOXA11-AS expression in KHOS cells could inhibit cell proliferation, while up-regulation of HOXA11-AS expression could promote cell proliferation *P<0.05,**P<0.01. (C) Down-regulation of HOXA11-AS expression in MG-63 cells could inhibit the growth of subcutaneous solid tumors in nude mice, while up-regulation of HOXA11-AS expression could promote the growth of subcutaneous solid tumors in nude mice. (D) Changes of tumor volume with time after inoculation of MG-63 cells of different groups **P<0.01. (E) Down-regulation of HOXA11-AS expression in KHOS cells could inhibit the growth of subcutaneous solid tumors in nude mice, while up-regulation of HOXA11-AS expression could promote the growth of subcutaneous solid tumors in nude mice. (F) Changes of tumor volume with time after inoculation of MG-63 cells of different groups.