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. 2019 May 16;11:4505–4518. doi: 10.2147/CMAR.S196025

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© 2019 Cao et al.

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HOXA11-AS could directly regulate the expression of miR-125-5p. (A) Construction of WT-HOXA11- AS and Mut-HOXA11-AS. (B) RT-PCR results showed that the expression level of miR-125a-5p in OS tissues was significantly lower than that in their adjacent tissues (**P<0.01). (C) Inhibiting the expression of HOXA11-AS in MG-63 cells could significantly increase the expression level of miR-125a-5p (**P<0.01). (D) Overexpression of HOXA11-AS in KHOS cells could significantly inhibit the expression of miR-125a-5p (**P<0.01).