(A) Localization of nuclear Gata6 (green) in control (top) or K5;Gata6 mutant skin (bottom). Arrows, Gata6 in upper follicle. Arrowheads, dilated sebaceous ducts. Magnified views also shown. (B) Lack of Gata6 (green) in early- (left) or mid-anagen (right) control follicles. On left, K79 (red) identifies early companion layer (arrow) (21). (C) Nuclear Gata6 (green, arrow) in upper domain of human hair follicle. Magnified view on right. (D) Control (left) and K5;Gata6 male mice (right), 2 weeks post-depilation. (E) The same mice at ~20 weeks of age. (F) Histology of untreated control and K5;Gata6 anagen skin at 4 weeks of age. Scale bars, 50 μm.