Table 1.
Multivariable model predicting receipt of at least 300 days of hydroxyurea among children with SCA with evidence of hydroxyurea use (N=4370 person-years).
| Predictor | Odds Ratio | 95% Confidence Interval | P-Value |
|---|---|---|---|
| Inpatient Visits | 0.77 | 0.73, 0.81 | <0.0001 |
| ED Visits | 1.01 | 0.99, 1.04 | 0.1982 |
| Outpatient Visits | 1.01 | 1.00, 1.02 | 0.0018 |
| Age | 0.93 | 0.91, 0.94 | <0.0001 |
| Sex | |||
| Male | Reference | Reference | Reference |
| Female | 0.92 | 0.78, 1.08 | 0.2803 |
| State | |||
| Illinois | Reference | Reference | Reference |
| Michigan | 1.12 | 0.83, 1.50 | 0.4635 |
| Louisiana | 0.93 | 0.71, 1.24 | 0.6339 |
| South Carolina | 0.55 | 0.39, 0.79 | 0.0010 |
| Texas | 0.78 | 0.59, 1.03 | 0.0754 |
| Florida | 0.96 | 0.74, 1.24 | 0.7567 |
| Year | |||
| 2005 | Reference | Reference | Reference |
| 2006 | 0.85 | 0.59, 1.22 | 0.3861 |
| 2007 | 0.90 | 0.63, 1.29 | 0.5669 |
| 2008 | 0.93 | 0.65, 1.32 | 0.6683 |
| 2009 | 0.67 | 0.47, 0.97 | 0.0311 |
| 2010 | 0.80 | 0.57, 1.12 | 0.1944 |
| 2011 | 0.69 | 0.49, 0.96 | 0.0273 |
| 2012 | 0.64 | 0.46, 0.89 | 0.0076 |